Cargando…
A nuclear factor-binding domain in the 5'-untranslated region of the amyloid precursor protein promoter: Implications for the regulation of gene expression
BACKGROUND: The extracellular deposition of aggregated amyloid β-protein is a neuropathological manifestation of Alzheimer disease and Down syndrome. The Amyloid β-protein is derived from a group of larger differentially spliced proteins, the amyloid protein precursors (APP). Data suggests that the...
Autores principales: | Vostrov, Alexander A, Taheny, Michael J, Izkhakov, Nerik, Quitschke, Wolfgang W |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828463/ https://www.ncbi.nlm.nih.gov/pubmed/20205906 http://dx.doi.org/10.1186/1756-0500-3-4 |
Ejemplares similares
-
Two adjacent nuclear factor-binding domains activate expression from the human PRNP promoter
por: Taheny, Michael J, et al.
Publicado: (2009) -
Novel 5′ Untranslated Region Directed Blockers of Iron-Regulatory Protein-1 Dependent Amyloid Precursor Protein Translation: Implications for Down Syndrome and Alzheimer's Disease
por: Bandyopadhyay, Sanghamitra, et al.
Publicado: (2013) -
The ODC 3′-Untranslated Region and 5′-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis
por: Nowotarski, Shannon L., et al.
Publicado: (2017) -
Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease
por: Long, Justin M., et al.
Publicado: (2018) -
Novel Adaptors of Amyloid Precursor Protein Intracellular Domain and Their Functional Implications
por: Chakrabarti, Arunabha, et al.
Publicado: (2012)