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Increased α-Defensins 1-3 Production by Dendritic Cells in HIV-Infected Individuals Is Associated with Slower Disease Progression

BACKGROUND: Defensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce α-defensins1-3 and that α-defensins1-3 modulate DC generation and maturation. Since DC-HIV interaction...

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Detalles Bibliográficos
Autores principales: Rodríguez-García, Marta, Climent, Núria, Oliva, Harold, Casanova, Víctor, Franco, Rafael, Leon, Agathe, Gatell, José M., García, Felipe, Gallart, Teresa
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828484/
https://www.ncbi.nlm.nih.gov/pubmed/20195543
http://dx.doi.org/10.1371/journal.pone.0009436