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Increased α-Defensins 1-3 Production by Dendritic Cells in HIV-Infected Individuals Is Associated with Slower Disease Progression
BACKGROUND: Defensins are natural endogenous antimicrobial peptides with potent anti-HIV activity and immuno-modulatory effects. We recently demonstrated that immature dendritic cells (DC) produce α-defensins1-3 and that α-defensins1-3 modulate DC generation and maturation. Since DC-HIV interaction...
Autores principales: | Rodríguez-García, Marta, Climent, Núria, Oliva, Harold, Casanova, Víctor, Franco, Rafael, Leon, Agathe, Gatell, José M., García, Felipe, Gallart, Teresa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828484/ https://www.ncbi.nlm.nih.gov/pubmed/20195543 http://dx.doi.org/10.1371/journal.pone.0009436 |
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