Goniothalamin-induced oxidative stress, DNA damage and apoptosis via caspase-2 independent and Bcl-2 independent pathways in Jurkat T-cells

Goniothalamin (GTN) isolated from Goniothalamus sp. has been demonstrated to induce apoptosis in a variety of cancer cell lines including Jurkat T leukemia cells. However, the mechanism of GTN-induced apoptosis upstream of mitochondria is still poorly defined. In this study, GTN caused a decrease in...

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Detalles Bibliográficos
Autores principales: Inayat-Hussain, S.H., Chan, K.M., Rajab, N.F., Din, L.B., Chow, S.C., Kizilors, A., Farzaneh, F., Williams, G.T.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828539/
https://www.ncbi.nlm.nih.gov/pubmed/20026395
http://dx.doi.org/10.1016/j.toxlet.2009.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828539/
https://www.ncbi.nlm.nih.gov/pubmed/20026395
http://dx.doi.org/10.1016/j.toxlet.2009.12.010

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