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The Folding Pathway of a Single Domain in a Multidomain Protein is not Affected by Its Neighbouring Domain

Domains are the structural, functional, and evolutionary components of proteins. Most folding studies to date have concentrated on the folding of single domains, but more than 70% of human proteins contain more than one domain, and interdomain interactions can affect both the stability and the foldi...

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Detalles Bibliográficos
Autores principales: Batey, Sarah, Clarke, Jane
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828540/
https://www.ncbi.nlm.nih.gov/pubmed/18371978
http://dx.doi.org/10.1016/j.jmb.2008.02.032