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AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

OBJECTIVE: Resveratrol, a natural polyphenolic compound that is found in grapes and red wine, increases metabolic rate, insulin sensitivity, mitochondrial biogenesis, and physical endurance and reduces fat accumulation in mice. Although it is thought that resveratrol targets Sirt1, this is controver...

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Detalles Bibliográficos
Autores principales: Um, Jee-Hyun, Park, Sung-Jun, Kang, Hyeog, Yang, Shutong, Foretz, Marc, McBurney, Michael W., Kim, Myung K., Viollet, Benoit, Chung, Jay H.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828647/
https://www.ncbi.nlm.nih.gov/pubmed/19934007
http://dx.doi.org/10.2337/db09-0482