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AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol
OBJECTIVE: Resveratrol, a natural polyphenolic compound that is found in grapes and red wine, increases metabolic rate, insulin sensitivity, mitochondrial biogenesis, and physical endurance and reduces fat accumulation in mice. Although it is thought that resveratrol targets Sirt1, this is controver...
Autores principales: | Um, Jee-Hyun, Park, Sung-Jun, Kang, Hyeog, Yang, Shutong, Foretz, Marc, McBurney, Michael W., Kim, Myung K., Viollet, Benoit, Chung, Jay H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828647/ https://www.ncbi.nlm.nih.gov/pubmed/19934007 http://dx.doi.org/10.2337/db09-0482 |
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