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Expression of hypoxia-inducible factor 1α in thyroid carcinomas

Hypoxia-inducible factor 1α (HIF-1α) is upregulated by hypoxia and oncogenic signalling in many solid tumours. Its regulation and function in thyroid carcinomas are unknown. We evaluated the regulation of HIF-1α and target gene expression in primary thyroid carcinomas and thyroid carcinoma cell line...

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Detalles Bibliográficos
Autores principales: Burrows, N, Resch, J, Cowen, R L, von Wasielewski, R, Hoang-Vu, C, West, C M, Williams, K J, Brabant, G
Formato: Texto
Lenguaje:English
Publicado: Society for Endocrinology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828807/
https://www.ncbi.nlm.nih.gov/pubmed/19808899
http://dx.doi.org/10.1677/ERC-08-0251