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A homology model of the pore domain of a voltage-gated calcium channel is consistent with available SCAM data

In the absence of x-ray structures of calcium channels, their homology models are used to rationalize experimental data and design new experiments. The modeling relies on sequence alignments between calcium and potassium channels. Zhen et al. (2005. J. Gen. Physiol. doi:10.1085/jgp.200509292) used t...

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Detalles Bibliográficos
Autores principales: Bruhova, Iva, Zhorov, Boris S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828909/
https://www.ncbi.nlm.nih.gov/pubmed/20176854
http://dx.doi.org/10.1085/jgp.200910288