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A homology model of the pore domain of a voltage-gated calcium channel is consistent with available SCAM data
In the absence of x-ray structures of calcium channels, their homology models are used to rationalize experimental data and design new experiments. The modeling relies on sequence alignments between calcium and potassium channels. Zhen et al. (2005. J. Gen. Physiol. doi:10.1085/jgp.200509292) used t...
Autores principales: | Bruhova, Iva, Zhorov, Boris S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828909/ https://www.ncbi.nlm.nih.gov/pubmed/20176854 http://dx.doi.org/10.1085/jgp.200910288 |
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