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Systematic mapping of the state dependence of voltage- and Ca(2+)-dependent inactivation using simple open-channel measurements
The state from which channel inactivation occurs is both biologically and mechanistically critical. For example, preferential closed-state inactivation is potentiated in certain Ca(2+) channel splice variants, yielding an enhancement of inactivation during action potential trains, which has importan...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828911/ https://www.ncbi.nlm.nih.gov/pubmed/20142518 http://dx.doi.org/10.1085/jgp.200910309 |