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Metabolic control of G1–S transition: cyclin E degradation by p53-induced activation of the ubiquitin–proteasome system
Cell cycle progression is precisely regulated by diverse extrinsic and intrinsic cellular factors. Previous genetic analysis in Drosophila melanogaster has shown that disruption of the mitochondrial electron transport chain activates a G1–S checkpoint as a result of a control of cyclin E by p53. Thi...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828916/ https://www.ncbi.nlm.nih.gov/pubmed/20176921 http://dx.doi.org/10.1083/jcb.200912024 |