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Directly probing the mechanical properties of the spindle and its matrix

Several recent models for spindle length regulation propose an elastic pole to pole spindle matrix that is sufficiently strong to bear or antagonize forces generated by microtubules and microtubule motors. We tested this hypothesis using microneedles to skewer metaphase spindles in Xenopus laevis eg...

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Detalles Bibliográficos
Autores principales: Gatlin, Jesse C., Matov, Alexandre, Danuser, Gaudenz, Mitchison, Timothy J., Salmon, Edward D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828919/
https://www.ncbi.nlm.nih.gov/pubmed/20176922
http://dx.doi.org/10.1083/jcb.200907110