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Directly probing the mechanical properties of the spindle and its matrix
Several recent models for spindle length regulation propose an elastic pole to pole spindle matrix that is sufficiently strong to bear or antagonize forces generated by microtubules and microtubule motors. We tested this hypothesis using microneedles to skewer metaphase spindles in Xenopus laevis eg...
Autores principales: | Gatlin, Jesse C., Matov, Alexandre, Danuser, Gaudenz, Mitchison, Timothy J., Salmon, Edward D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828919/ https://www.ncbi.nlm.nih.gov/pubmed/20176922 http://dx.doi.org/10.1083/jcb.200907110 |
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