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Glycolipid Trafficking in Drosophila Undergoes Pathway Switching in Response to Aberrant Cholesterol Levels

In lipid storage diseases, the intracellular trafficking of sphingolipids is altered by conditions of aberrant cholesterol accumulation. Drosophila has been used recently to model lipid storage diseases, but the effects of sterol accumulation on sphingolipid trafficking are not known in the fly, and...

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Detalles Bibliográficos
Autores principales: Hortsch, Ralf, Lee, Esther, Erathodiyil, Nandanan, Hebbar, Sarita, Steinert, Steffen, Lee, Jun Yu, Chua, Doreen See Kin, Kraut, Rachel
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828964/
https://www.ncbi.nlm.nih.gov/pubmed/20053687
http://dx.doi.org/10.1091/mbc.E09-01-0005