The Late Endosome is Essential for mTORC1 Signaling

The multisubunit mTORC1 complex integrates signals from growth factors and nutrients to regulate protein synthesis, cell growth, and autophagy. To examine how endocytic trafficking might be involved in nutrient regulation of mTORC1, we perturbed specific endocytic trafficking pathways and measured m...

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Detalles Bibliográficos
Autores principales: Flinn, Rory J., Yan, Ying, Goswami, Sumanta, Parker, Peter J., Backer, Jonathan M.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828969/
https://www.ncbi.nlm.nih.gov/pubmed/20053679
http://dx.doi.org/10.1091/mbc.E09-09-0756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828969/
https://www.ncbi.nlm.nih.gov/pubmed/20053679
http://dx.doi.org/10.1091/mbc.E09-09-0756

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