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Mutation of mitochondria genome: trigger of somatic cell transforming to cancer cell
Nearly 80 years ago, scientist Otto Warburg originated a hypothesis that the cause of cancer is primarily a defect in energy metabolism. Following studies showed that mitochondria impact carcinogenesis to remodel somatic cells to cancer cells through modifying the genome, through maintenance the tum...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828995/ https://www.ncbi.nlm.nih.gov/pubmed/20181100 http://dx.doi.org/10.1186/1755-7682-3-4 |