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Bias correction and Bayesian analysis of aggregate counts in SAGE libraries
BACKGROUND: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation process may allow for multiple tags to be generated from a given mRNA transcript. The probability of forming a tag varies with...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829012/ https://www.ncbi.nlm.nih.gov/pubmed/20128916 http://dx.doi.org/10.1186/1471-2105-11-72 |