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Bias correction and Bayesian analysis of aggregate counts in SAGE libraries

BACKGROUND: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation process may allow for multiple tags to be generated from a given mRNA transcript. The probability of forming a tag varies with...

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Detalles Bibliográficos
Autores principales: Zaretzki, Russell L, Gilchrist, Michael A, Briggs, William M, Armagan, Artin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829012/
https://www.ncbi.nlm.nih.gov/pubmed/20128916
http://dx.doi.org/10.1186/1471-2105-11-72