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Structural diversity and evolution of the N-terminal isoform-specific region of ecdysone receptor-A and -B1 isoforms in insects

BACKGROUND: The ecdysone receptor (EcR) regulates various cellular responses to ecdysteroids during insect development. Insects have multiple EcR isoforms with different N-terminal A/B domains that contain the isoform-specific activation function (AF)-1 region. Although distinct physiologic function...

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Detalles Bibliográficos
Autores principales: Watanabe, Takayuki, Takeuchi, Hideaki, Kubo, Takeo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829036/
https://www.ncbi.nlm.nih.gov/pubmed/20152013
http://dx.doi.org/10.1186/1471-2148-10-40