Mycobacterium tuberculosis Peptides Presented by HLA-E Molecules Are Targets for Human CD8(+) T-Cells with Cytotoxic as well as Regulatory Activity

Tuberculosis (TB) is an escalating global health problem and improved vaccines against TB are urgently needed. HLA-E restricted responses may be of interest for vaccine development since HLA-E displays very limited polymorphism (only 2 coding variants exist), and is not down-regulated by HIV-infecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Joosten, Simone A., van Meijgaarden, Krista E., van Weeren, Pascale C., Kazi, Fatima, Geluk, Annemieke, Savage, Nigel D. L., Drijfhout, Jan W., Flower, Darren R., Hanekom, Willem A., Klein, Michèl R., Ottenhoff, Tom H. M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829052/
https://www.ncbi.nlm.nih.gov/pubmed/20195504
http://dx.doi.org/10.1371/journal.ppat.1000782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829052/
https://www.ncbi.nlm.nih.gov/pubmed/20195504
http://dx.doi.org/10.1371/journal.ppat.1000782

Ejemplares similares