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HIV Controller CD4+ T Cells Respond to Minimal Amounts of Gag Antigen Due to High TCR Avidity

HIV controllers are rare individuals who spontaneously control HIV replication in the absence of antiretroviral treatment. Emerging evidence indicates that HIV control is mediated through very active cellular immune responses, though how such responses can persist over time without immune exhaustion...

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Detalles Bibliográficos
Autores principales: Vingert, Benoît, Perez-Patrigeon, Santiago, Jeannin, Patricia, Lambotte, Olivier, Boufassa, Faroudy, Lemaître, Fabrice, Kwok, William W., Theodorou, Ioannis, Delfraissy, Jean-François, Thèze, Jacques, Chakrabarti, Lisa A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829066/
https://www.ncbi.nlm.nih.gov/pubmed/20195518
http://dx.doi.org/10.1371/journal.ppat.1000780