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Broadly Protective Monoclonal Antibodies against H3 Influenza Viruses following Sequential Immunization with Different Hemagglutinins

As targets of adaptive immunity, influenza viruses are characterized by the fluidity with which they respond to the selective pressure applied by neutralizing antibodies. This mutability of structural determinants of protective immunity is the obstacle in developing universal influenza vaccines. Tow...

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Detalles Bibliográficos
Autores principales: Wang, Taia T., Tan, Gene S., Hai, Rong, Pica, Natalie, Petersen, Erin, Moran, Thomas M., Palese, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829068/
https://www.ncbi.nlm.nih.gov/pubmed/20195520
http://dx.doi.org/10.1371/journal.ppat.1000796