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Broadly Protective Monoclonal Antibodies against H3 Influenza Viruses following Sequential Immunization with Different Hemagglutinins
As targets of adaptive immunity, influenza viruses are characterized by the fluidity with which they respond to the selective pressure applied by neutralizing antibodies. This mutability of structural determinants of protective immunity is the obstacle in developing universal influenza vaccines. Tow...
Autores principales: | Wang, Taia T., Tan, Gene S., Hai, Rong, Pica, Natalie, Petersen, Erin, Moran, Thomas M., Palese, Peter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829068/ https://www.ncbi.nlm.nih.gov/pubmed/20195520 http://dx.doi.org/10.1371/journal.ppat.1000796 |
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