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Co-Expression of DevR and DevR(N)-Aph Proteins Is Associated with Hypoxic Adaptation Defect and Virulence Attenuation of Mycobacterium tuberculosis

BACKGROUND: The DevR response regulator is implicated in both hypoxic adaptation and virulence of Mycobacterium tuberculosis (M. tb). DevR regulon genes are powerfully induced in vivo implicating them in bacterial adaptation to host control strategies. A better understanding of DevR function will il...

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Detalles Bibliográficos
Autores principales: Majumdar, Shyamasree De, Sharma, Deepak, Vashist, Atul, Kaur, Kohinoor, Taneja, Neetu Kumra, Chauhan, Santosh, Challu, Vijay K., Ramanathan, V. D., Balasangameshwara, V., Kumar, Prahlad, Tyagi, Jaya Sivaswami
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829086/
https://www.ncbi.nlm.nih.gov/pubmed/20195478
http://dx.doi.org/10.1371/journal.pone.0009448