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Direct conversion of fibroblasts to functional neurons by defined factors
Cellular differentiation and lineage commitment are considered robust and irreversible processes during development. Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four transcription factors. This raised the question of whether...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829121/ https://www.ncbi.nlm.nih.gov/pubmed/20107439 http://dx.doi.org/10.1038/nature08797 |