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Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A(1) receptor ligands
BACKGROUND AND PURPOSE: The introduction of fluorescence-based techniques, and in particular the development of fluorescent ligands, has allowed the study of G protein-coupled receptor pharmacology at the single cell and single molecule level. This study evaluated how the physicochemical nature of t...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829203/ https://www.ncbi.nlm.nih.gov/pubmed/20105183 http://dx.doi.org/10.1111/j.1476-5381.2009.00488.x |