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Thr(435) phosphorylation regulates RelA (p65) NF-κB subunit transactivation

Phosphorylation of the RelA (p65) NF-κB (nuclear factor κB) subunit has been previously shown to modulate its ability to induce or repress transcription. In the present study we have investigated the consequences of Thr(435) phosphorylation within the C-terminal transactivation domain of RelA. We co...

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Detalles Bibliográficos
Autores principales: O'Shea, John M., Perkins, Neil D.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829238/
https://www.ncbi.nlm.nih.gov/pubmed/20001970
http://dx.doi.org/10.1042/BJ20091630