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Fas receptor is required for estrogen deficiency-induced bone loss in mice

Bone mass is determined by bone cell differentiation, activity and death, which mainly occur through apoptosis. Apoptosis can be triggered by death receptor Fas (CD95), expressed on osteoblasts and osteoclasts and may be regulated by estrogen. We have previously shown that signaling through Fas inhi...

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Detalles Bibliográficos
Autores principales: Kovacic, Natasa, Grcevic, Danka, Katavic, Vedran, Lukic, Ivan Kresimir, Grubisic, Vladimir, Mihovilovic, Karlo, Cvija, Hrvoje, Croucher, Peter Ian, Marusic, Ana
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829329/
https://www.ncbi.nlm.nih.gov/pubmed/20084056
http://dx.doi.org/10.1038/labinvest.2009.144