Cargando…

A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma

BACKGROUND: DNA-methyltransferase (DNMT)-3A plays an important role in the development of embryogenesis and the generation of aberrant methylation in carcinogenesis. The aim of this study was to investigate the role of a DNMT3A promoter genetic variant on its transcriptional activity and to evaluate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Hong, Liu, Dongsheng, Qiu, Xuemei, Qiao, Fengchang, Wu, Qingxiang, Su, Xianwei, Zhang, Feng, Song, Yunwei, Zhao, Zhujiang, Xie, Wei
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829483/ https://www.ncbi.nlm.nih.gov/pubmed/20128888 http://dx.doi.org/10.1186/1741-7015-8-12

Ejemplares similares

Risk-Association of DNA Methyltransferases Polymorphisms with Gastric Cancer in the Southern Chinese Population
por: Yang, Xue-Xi, et al.
Publicado: (2012)

Depletion of DNMT3A Suppressed Cell Proliferation and Restored PTEN in Hepatocellular Carcinoma Cell
por: Zhao, Zhujiang, et al.
Publicado: (2010)

Reduced miR-29a-3p expression is linked to the cell proliferation and cell migration in gastric cancer
por: Zhao, Zhujiang, et al.
Publicado: (2015)

Silenced PITX1 promotes chemotherapeutic resistance to 5-fluorocytosine and cisplatin in gastric cancer cells
por: Shen, Xiaohui, et al.
Publicado: (2019)

Polymorphism of DNA Methyltransferase 3b and Association with Development and Prognosis in Gastric Cancer
por: Wang, Chuan, et al.
Publicado: (2015)

DNA methyltransferase 3A gene polymorphism contributes to daily life stress susceptibility
por: Barliana, Melisa I, et al.
Publicado: (2017)

Association between DNA Methyltransferases 3B Gene Polymorphisms and the Susceptibility to Acute Myeloid Leukemia in Chinese Han Population
por: Zheng, Qin, et al.
Publicado: (2013)

Polymorphisms of the DNA Methyltransferase 1 Gene Predict Survival of Gastric Cancer Patients Receiving Tumorectomy
por: Jia, Zhifang, et al.
Publicado: (2016)

XPF-673C>T Polymorphism Effect on the Susceptibility to Esophageal Cancer in Chinese Population
por: Liu, Yingwen, et al.
Publicado: (2014)

Promoter polymorphisms of DNMT3B and the risk of colorectal cancer in Chinese: a case-control study
por: Fan, Hong, et al.
Publicado: (2008)

Polymorphisms of the DNA Methyltransferase 1 Associated with Reduced Risks of Helicobacter pylori Infection and Increased Risks of Gastric Atrophy
por: Jiang, Jing, et al.
Publicado: (2012)

DNA Methyltransferase Candidate Polymorphisms, Imprinting Methylation, and Birth Outcome
por: Haggarty, Paul, et al.
Publicado: (2013)

The Mycobacterial DNA Methyltransferase HsdM Decreases Intrinsic Isoniazid Susceptibility
por: Hu, Xinling, et al.
Publicado: (2021)

DNA methyltransferase 3A isoform b contributes to repressing E-cadherin through cooperation of DNA methylation and H3K27/H3K9 methylation in EMT-related metastasis of gastric cancer
por: Cui, He, et al.
Publicado: (2018)

Genetic Polymorphisms of Catechol-O-Methyltransferase Modify the Neurobehavioral Effects of Mercury in Children
por: Woods, James S., et al.
Publicado: (2014)

Recent progress in DNA methyltransferase inhibitors as anticancer agents
por: Zhang, Zhixiong, et al.
Publicado: (2022)

Human Intelligence and Polymorphisms in the DNA Methyltransferase Genes Involved in Epigenetic Marking
por: Haggarty, Paul, et al.
Publicado: (2010)

Modified Adenosines Sensitize Glioblastoma Cells to Temozolomide by Affecting DNA Methyltransferases
por: Proto, Maria Chiara, et al.
Publicado: (2022)

Involvement of Human Histamine N-Methyltransferase Gene Polymorphisms in Susceptibility to Atopic Dermatitis in Korean Children
por: Lee, Hee Seon, et al.
Publicado: (2012)

The epigenetic modifier lysine methyltransferase 2C is frequently mutated in gastric remnant carcinoma
por: Sun, Bo, et al.
Publicado: (2023)

Idiopathic male infertility and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking
por: Tang, Qiuqin, et al.
Publicado: (2017)

Association of the DNA Methyltransferase and Folate Cycle Enzymes’ Gene Polymorphisms with Coronary Restenosis
por: Timizheva, Kalima B., et al.
Publicado: (2022)

DNA methylation and DNA methyltransferases
por: Edwards, John R., et al.
Publicado: (2017)

A Novel Functional TagSNP Rs7560488 in the DNMT3A1 Promoter Is Associated with Susceptibility to Gastric Cancer by Modulating Promoter Activity
por: Wu, Huazhang, et al.
Publicado: (2014)

PSCA polymorphisms and gastric cancer susceptibility in an eastern Chinese population
por: Qiu, Li-Xin, et al.
Publicado: (2016)

LIN28A gene polymorphisms modify neuroblastoma susceptibility: A four‐centre case‐control study
por: Hua, Rui‐Xi, et al.
Publicado: (2019)

Erratum: Involvement of Human Histamine N-Methyltransferase Gene Polymorphisms in Susceptibility to Atopic Dermatitis in Korean Children
por: Lee, Hee Seon, et al.
Publicado: (2013)

47 Involvement of Human Histamine N-Methyltransferase Gene Polymorphisms in Susceptibility to Atopic Dermatitis in Korean Children
por: Lee, Hee Seon, et al.
Publicado: (2012)

Functional Polymorphisms in Interleukin-23 Receptor and Susceptibility to Esophageal Squamous Cell Carcinoma in Chinese Population
por: Ni, Bin, et al.
Publicado: (2014)

Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer
por: Piao, Ying, et al.
Publicado: (2015)

Genetic polymorphisms of NAMPT related with susceptibility to esophageal Squamous cell carcinoma
por: Zhang, Chuanzhen, et al.
Publicado: (2015)

Dietary Flavones as Dual Inhibitors of DNA Methyltransferases and Histone Methyltransferases
por: Kanwal, Rajnee, et al.
Publicado: (2016)

Association between the catechol-o-methyltransferase val158met polymorphism with susceptibility and severity of carpal tunnel syndrome
por: Erkol İnal, E, et al.
Publicado: (2016)

Catechol-O-Methyltransferase Gene Polymorphism Modifies the Effect of Coffee Intake on Incidence of Acute Coronary Events
por: Happonen, Pertti, et al.
Publicado: (2006)

Combined effects of cigarette smoking, DNA methyltransferase 3B genetic polymorphism, and DNA damage on lung cancer
por: Huang, Chia-Chen, et al.
Publicado: (2021)

Molecular characterization and transcription analysis of DNA methyltransferase genes in tomato (Solanum lycopersicum)
por: Guo, Xuhu, et al.
Publicado: (2020)

Thiopurine S-Methyltransferase and Methylenetetrahydrofolate Reductase Polymorphisms in Leukemia
por: KÜPELİ, Serhan
Publicado: (2015)

Thiopurine S-Methyltransferase Polymorphisms in Korean Dermatologic Patients
por: Lee, Minseok, et al.
Publicado: (2017)

DNA methyltransferases and their roles in tumorigenesis
por: Zhang, Wu, et al.
Publicado: (2017)

DNA Methyltransferases in Depression: An Update
por: Duan, Zhenghao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3g732dsomk7dd15mcm7705tkgf