Stiff limb syndrome: a case report
INTRODUCTION: Stiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyri...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829520/ https://www.ncbi.nlm.nih.gov/pubmed/20205913 http://dx.doi.org/10.1186/1757-1626-3-60 |
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author | Hajjioui, Abderrazak Benbouazza, Karima Faris, Mohamed El Alaoui Missaoui, Amina Hassouni, Najia Hajjaj |
author_facet | Hajjioui, Abderrazak Benbouazza, Karima Faris, Mohamed El Alaoui Missaoui, Amina Hassouni, Najia Hajjaj |
author_sort | Hajjioui, Abderrazak |
collection | PubMed |
description | INTRODUCTION: Stiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient diagnosed by neurological symptoms of stiff limb syndrome with a good outcome after treatment, and a review of the related literature. CASE PRESENTATION: A 49-year-old male patient presented with a progressive stiffness and painful spasms of his both legs resulting in a difficulty of standing up and walking. The diagnosis of stiff limb syndrome was supported by the dramatically positive response to treatment using diazepam 25 mg/day and baclofen 30 mg/day. CONCLUSION: This clinical case highlights the importance of a therapeutic test to confirm the diagnosis of stiff limb syndrome especially when there is a high clinical suspicion with unremarkable electromyography |
format | Text |
id | pubmed-2829520 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-28295202010-02-28 Stiff limb syndrome: a case report Hajjioui, Abderrazak Benbouazza, Karima Faris, Mohamed El Alaoui Missaoui, Amina Hassouni, Najia Hajjaj Cases J Case Report INTRODUCTION: Stiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient diagnosed by neurological symptoms of stiff limb syndrome with a good outcome after treatment, and a review of the related literature. CASE PRESENTATION: A 49-year-old male patient presented with a progressive stiffness and painful spasms of his both legs resulting in a difficulty of standing up and walking. The diagnosis of stiff limb syndrome was supported by the dramatically positive response to treatment using diazepam 25 mg/day and baclofen 30 mg/day. CONCLUSION: This clinical case highlights the importance of a therapeutic test to confirm the diagnosis of stiff limb syndrome especially when there is a high clinical suspicion with unremarkable electromyography BioMed Central 2010-02-12 /pmc/articles/PMC2829520/ /pubmed/20205913 http://dx.doi.org/10.1186/1757-1626-3-60 Text en Copyright ©2010 Hajjioui et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Hajjioui, Abderrazak Benbouazza, Karima Faris, Mohamed El Alaoui Missaoui, Amina Hassouni, Najia Hajjaj Stiff limb syndrome: a case report |
title | Stiff limb syndrome: a case report |
title_full | Stiff limb syndrome: a case report |
title_fullStr | Stiff limb syndrome: a case report |
title_full_unstemmed | Stiff limb syndrome: a case report |
title_short | Stiff limb syndrome: a case report |
title_sort | stiff limb syndrome: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829520/ https://www.ncbi.nlm.nih.gov/pubmed/20205913 http://dx.doi.org/10.1186/1757-1626-3-60 |
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