Stiff limb syndrome: a case report

INTRODUCTION: Stiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyri...

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Autores principales: Hajjioui, Abderrazak, Benbouazza, Karima, Faris, Mohamed El Alaoui, Missaoui, Amina, Hassouni, Najia Hajjaj
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829520/
https://www.ncbi.nlm.nih.gov/pubmed/20205913
http://dx.doi.org/10.1186/1757-1626-3-60
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author Hajjioui, Abderrazak
Benbouazza, Karima
Faris, Mohamed El Alaoui
Missaoui, Amina
Hassouni, Najia Hajjaj
author_facet Hajjioui, Abderrazak
Benbouazza, Karima
Faris, Mohamed El Alaoui
Missaoui, Amina
Hassouni, Najia Hajjaj
author_sort Hajjioui, Abderrazak
collection PubMed
description INTRODUCTION: Stiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient diagnosed by neurological symptoms of stiff limb syndrome with a good outcome after treatment, and a review of the related literature. CASE PRESENTATION: A 49-year-old male patient presented with a progressive stiffness and painful spasms of his both legs resulting in a difficulty of standing up and walking. The diagnosis of stiff limb syndrome was supported by the dramatically positive response to treatment using diazepam 25 mg/day and baclofen 30 mg/day. CONCLUSION: This clinical case highlights the importance of a therapeutic test to confirm the diagnosis of stiff limb syndrome especially when there is a high clinical suspicion with unremarkable electromyography
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spelling pubmed-28295202010-02-28 Stiff limb syndrome: a case report Hajjioui, Abderrazak Benbouazza, Karima Faris, Mohamed El Alaoui Missaoui, Amina Hassouni, Najia Hajjaj Cases J Case Report INTRODUCTION: Stiff limb syndrome is a clinical feature of the stiff person syndrome, which is a rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms that involve axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient diagnosed by neurological symptoms of stiff limb syndrome with a good outcome after treatment, and a review of the related literature. CASE PRESENTATION: A 49-year-old male patient presented with a progressive stiffness and painful spasms of his both legs resulting in a difficulty of standing up and walking. The diagnosis of stiff limb syndrome was supported by the dramatically positive response to treatment using diazepam 25 mg/day and baclofen 30 mg/day. CONCLUSION: This clinical case highlights the importance of a therapeutic test to confirm the diagnosis of stiff limb syndrome especially when there is a high clinical suspicion with unremarkable electromyography BioMed Central 2010-02-12 /pmc/articles/PMC2829520/ /pubmed/20205913 http://dx.doi.org/10.1186/1757-1626-3-60 Text en Copyright ©2010 Hajjioui et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hajjioui, Abderrazak
Benbouazza, Karima
Faris, Mohamed El Alaoui
Missaoui, Amina
Hassouni, Najia Hajjaj
Stiff limb syndrome: a case report
title Stiff limb syndrome: a case report
title_full Stiff limb syndrome: a case report
title_fullStr Stiff limb syndrome: a case report
title_full_unstemmed Stiff limb syndrome: a case report
title_short Stiff limb syndrome: a case report
title_sort stiff limb syndrome: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829520/
https://www.ncbi.nlm.nih.gov/pubmed/20205913
http://dx.doi.org/10.1186/1757-1626-3-60
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