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Histone H3 lysine 4 methylation is associated with the transcriptional reprogramming efficiency of somatic nuclei by oocytes

BACKGROUND: When the nuclei of mammalian somatic cells are transplanted to amphibian oocytes in the first meiotic prophase, they are rapidly induced to begin transcribing several pluripotency genes, including Sox2 and Oct4. The more differentiated the donor cells of the nuclei, the longer it takes f...

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Detalles Bibliográficos
Autores principales: Murata, Kazutaka, Kouzarides, Tony, Bannister, Andrew J, Gurdon, John B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829560/
https://www.ncbi.nlm.nih.gov/pubmed/20181087
http://dx.doi.org/10.1186/1756-8935-3-4