Loss of estrogen receptor β decreases mitochondrial energetic potential and increases thrombogenicity of platelets in aged female mice

Platelets derived from aged (reproductively senescent) female mice with genetic deletion of estrogen receptor beta (βER) are more thrombogenic than those from age-matched wild-type (WT) mice. Intracellular processes contributing to this increased thrombogenicity are not known. Experiments were desig...

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Detalles Bibliográficos
Autores principales: Jayachandran, Muthuvel, Preston, Claudia C., Hunter, Larry W., Jahangir, Arshad, Owen, Whyte G., Korach, Kenneth S., Miller, Virginia M.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829645/
https://www.ncbi.nlm.nih.gov/pubmed/19908165
http://dx.doi.org/10.1007/s11357-009-9119-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829645/
https://www.ncbi.nlm.nih.gov/pubmed/19908165
http://dx.doi.org/10.1007/s11357-009-9119-y

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