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Loss of estrogen receptor β decreases mitochondrial energetic potential and increases thrombogenicity of platelets in aged female mice
Platelets derived from aged (reproductively senescent) female mice with genetic deletion of estrogen receptor beta (βER) are more thrombogenic than those from age-matched wild-type (WT) mice. Intracellular processes contributing to this increased thrombogenicity are not known. Experiments were desig...
Autores principales: | Jayachandran, Muthuvel, Preston, Claudia C., Hunter, Larry W., Jahangir, Arshad, Owen, Whyte G., Korach, Kenneth S., Miller, Virginia M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829645/ https://www.ncbi.nlm.nih.gov/pubmed/19908165 http://dx.doi.org/10.1007/s11357-009-9119-y |
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