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Frequent Promoter Hypermethylation of the APC and RASSF1A Tumour Suppressors in Parathyroid Tumours

BACKGROUND: Parathyroid adenomas constitute the most common entity in primary hyperparathyroidism, and although recent advances have been made regarding the underlying genetic cause of these lesions, very little data on epigenetic alterations in this tumour type exists. In this study, we have determ...

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Detalles Bibliográficos
Autores principales: Juhlin, C. Christofer, Kiss, Nimrod B., Villablanca, Andrea, Haglund, Felix, Nordenström, Jörgen, Höög, Anders, Larsson, Catharina
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830427/
https://www.ncbi.nlm.nih.gov/pubmed/20208994
http://dx.doi.org/10.1371/journal.pone.0009472