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Increasing Alternative Promoter Repertories Is Positively Associated with Differential Expression and Disease Susceptibility

BACKGROUND: Alternative Promoter (AP) usages have been shown to enable diversified transcriptional regulation of individual gene in a context-specific (e.g., pathway, cell lineage, tissue type, and development stage et. ac.) way. Aberrant uses of APs have been directly linked to mechanism of certain...

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Detalles Bibliográficos
Autor principal: Liu, Song
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830428/
https://www.ncbi.nlm.nih.gov/pubmed/20208995
http://dx.doi.org/10.1371/journal.pone.0009482