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Kinetic Modeling Reveals a Common Death Niche for Newly Formed and Mature B Cells
BACKGROUND: B lymphocytes are subject to elimination following strong BCR ligation in the absence of appropriate second signals, and this mechanism mediates substantial cell losses during late differentiation steps in the bone marrow and periphery. Mature B cells may also be eliminated through this...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830485/ https://www.ncbi.nlm.nih.gov/pubmed/20209168 http://dx.doi.org/10.1371/journal.pone.0009497 |