Transforming Growth Factor-β (TGFβ)-mediated Phosphorylation of hnRNP E1 Induces EMT via Transcript Selective Translational Induction of Dab2 and ILEI

TGFβ induces epithelial-mesenchymal transdifferentiation (EMT) accompanied by cellular differentiation and migration. Despite extensive transcriptomic profiling, identification of TGFβ-inducible, EMT-specific genes has met with limited success. Here, we identify a post-transcriptional pathway by whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaudhury, Arindam, Hussey, George S., Ray, Partho S, Jin, Ge, Fox, Paul L., Howe, Philip H.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830561/
https://www.ncbi.nlm.nih.gov/pubmed/20154680
http://dx.doi.org/10.1038/ncb2029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830561/
https://www.ncbi.nlm.nih.gov/pubmed/20154680
http://dx.doi.org/10.1038/ncb2029

Ejemplares similares