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Evidence for neuroendocrine function of a unique splicing form of TCF7L2 in human brain, islets and gut

AIMS/HYPOTHESIS: Variants in the TCF7L2 gene remain the strongest genetic associations with increased risk of type 2 diabetes. Recently, we identified a unique splicing form of TCF7L2 expressed in pancreatic islets, pancreas and colon and detected by assay ‘ex13-13b’. The expression of ex13-13b stro...

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Detalles Bibliográficos
Autores principales: Prokunina-Olsson, L., Hall, J. L.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830605/
https://www.ncbi.nlm.nih.gov/pubmed/20033802
http://dx.doi.org/10.1007/s00125-009-1640-0