Cargando…

Novel siRNA Delivery System to Target Podocytes In Vivo

Podocytes are injured in several glomerular diseases. To alter gene expression specifically in podocytes in vivo, we took advantage of their active endocytotic machinery and developed a method for the targeted delivery of small interfering ribonucleic acids (siRNA). We generated an anti-mouse podocy...

Descripción completa

Detalles Bibliográficos
Autores principales: Hauser, Peter V., Pippin, Jeffrey W., Kaiser, Cora, Krofft, Ronald D., Brinkkoetter, Paul T., Hudkins, Kelly L., Kerjaschki, Dontscho, Reiser, Jochen, Alpers, Charles E., Shankland, Stuart J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830889/
https://www.ncbi.nlm.nih.gov/pubmed/20209128
http://dx.doi.org/10.1371/journal.pone.0009463