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Immunohistochemical analysis of oxidative stress and DNA repair proteins in normal mammary and breast cancer tissues

BACKGROUND: During the course of normal cellular metabolism, oxygen is consumed and reactive oxygen species (ROS) are produced. If not effectively dissipated, ROS can accumulate and damage resident proteins, lipids, and DNA. Enzymes involved in redox regulation and DNA repair dissipate ROS and repai...

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Detalles Bibliográficos
Autores principales: Curtis, Carol D, Thorngren, Daniel L, Nardulli, Ann M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830938/
https://www.ncbi.nlm.nih.gov/pubmed/20064251
http://dx.doi.org/10.1186/1471-2407-10-9