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Characterization of a molecular switch system that regulates gene expression in mammalian cells through a small molecule

BACKGROUND: Molecular switch systems that activate gene expression by a small molecule are effective technologies that are widely used in applied biological research. Nuclear receptors are valuable candidates for these regulation systems due to their functional role as ligand activated transcription...

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Detalles Bibliográficos
Autores principales: Taylor, Jennifer L, Rohatgi, Priyanka, Spencer, H Trent, Doyle, Donald F, Azizi, Bahareh
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831033/
https://www.ncbi.nlm.nih.gov/pubmed/20167077
http://dx.doi.org/10.1186/1472-6750-10-15