Role of STAT3 in In Vitro Transformation Triggered by TRK Oncogenes

TRK oncoproteins are chimeric versions of the NTRK1/NGF receptor and display constitutive tyrosine kinase activity leading to transformation of NIH3T3 cells and neuronal differentiation of PC12 cells. Signal Transducer and Activator of Transcription (STAT) 3 is activated in response to cytokines and...

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Detalles Bibliográficos
Autores principales: Miranda, Claudia, Fumagalli, Tiziana, Anania, Maria Chiara, Vizioli, Maria Grazia, Pagliardini, Sonia, Pierotti, Marco A., Greco, Angela
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831059/
https://www.ncbi.nlm.nih.gov/pubmed/20209132
http://dx.doi.org/10.1371/journal.pone.0009446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831059/
https://www.ncbi.nlm.nih.gov/pubmed/20209132
http://dx.doi.org/10.1371/journal.pone.0009446

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