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Role of Spastin in Apical Domain Control along the Rhabdomere Elongation in Drosophila Photoreceptor

BACKGROUND: Mutations in spastin are the most common cause of hereditary spastin paraplegia, a neurodegenerative disease. In this study, the role of spastin was examined in Drosophila photoreceptor development. METHODOLOGY/PRINCIPAL FINDINGS: The spastin mutation in developing pupal eyes causes a mi...

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Detalles Bibliográficos
Autores principales: Chen, Geng, League, Garrett P., Nam, Sang-Chul
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831062/
https://www.ncbi.nlm.nih.gov/pubmed/20209135
http://dx.doi.org/10.1371/journal.pone.0009480