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Effect of Pharmaceutical Potential Endocrine Disruptor Compounds on Protein Disulfide Isomerase Reductase Activity Using Di-Eosin-Oxidized-Glutathion

BACKGROUND: Protein Disulfide Isomerase (PDI) in the endoplasmic reticulum of all cells catalyzes the rearrangement of disulfide bridges during folding of membrane and secreted proteins. As PDI is also known to bind various molecules including hormones such as estradiol and thyroxin, we considered t...

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Detalles Bibliográficos
Autores principales: Klett, Danièle, Cahoreau, Claire, Villeret, Mélanie, Combarnous, Yves
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831067/
https://www.ncbi.nlm.nih.gov/pubmed/20209080
http://dx.doi.org/10.1371/journal.pone.0009507