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Characterization of D-Cyclin Proteins in Hematolymphoid Neoplasms: Lack of Specificity of Cyclins D2 and D3 Expression in Lymphoma Subtypes

D-cyclin proteins play a central role in cell cycle regulation and are involved in the pathogenesis of lymphomas. In mantle cell lymphoma, the t(11;14) translocation leads to the overexpression of cyclin D1, in addition to which cyclin D1-negative mantle cell lymphoma that overexpress cyclin D2 or D...

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Detalles Bibliográficos
Autores principales: Metcalf, Ryan A, Zhao, Shuchun, Anderson, Matthew W, Lu, Zhi Shun, Galperin, Ilana, Marinelli, Robert J, Cherry, Athena M, Lossos, Izidore S, Natkunam, Yasodha
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831151/
https://www.ncbi.nlm.nih.gov/pubmed/20062012
http://dx.doi.org/10.1038/modpathol.2009.173