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Adenovirus-mediated stromal cell-derived factor-1 alpha gene transfer improves cardiac structure and function after experimental myocardial infarction through angiogenic and antifibrotic actions

Stromal cell-derived factor 1α (SDF-1) is not only a major chemotactic factor, but also an inducer of angiogenesis. The effects of SDF-1α on the left ventricular remodeling in a rat myocardial infarction (MI) model were analyzed. Myocardial infarction was induced by ligation of the left coronary art...

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Detalles Bibliográficos
Autores principales: Tang, Junming, Wang, Jianing, Song, Hongxian, Huang, Yongzhang, Yang, Jianye, Kong, Xia, Guo, Linyun, Zheng, Fei, Zhang, Lei
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831180/
https://www.ncbi.nlm.nih.gov/pubmed/19653123
http://dx.doi.org/10.1007/s11033-009-9642-z