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Testing the theory of immune selection in cancers that break the rules of transplantation

Modification of cancer cells likely to reduce their immunogenicity, including loss or down-regulation of MHC molecules, is now well documented and has become the main support for the concept of immune surveillance. The evidence that these modifications, in fact, result from selection by the immune s...

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Detalles Bibliográficos
Autores principales: Fassati, Ariberto, Mitchison, N. Avrion
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831185/
https://www.ncbi.nlm.nih.gov/pubmed/20033157
http://dx.doi.org/10.1007/s00262-009-0809-1