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The low-virulent African swine fever virus (ASFV/NH/P68) induces enhanced expression and production of relevant regulatory cytokines (IFNα, TNFα and IL12p40) on porcine macrophages in comparison to the highly virulent ASFV/L60

The impact of infection by the low-virulent ASFV/NH/P68 (NHV) and the highly virulent ASFV/L60 (L60) isolates on porcine macrophages was assessed through the quantification of IFNα, TNFα, IL12p40, TGFβ and ASFV genes by real-time PCR at 2, 4 and 6 h post-infection. Increased IFNα, TNFα and IL12p40 e...

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Detalles Bibliográficos
Autores principales: Gil, S., Sepúlveda, N., Albina, E., Leitão, A., Martins, C.
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831186/
https://www.ncbi.nlm.nih.gov/pubmed/18787755
http://dx.doi.org/10.1007/s00705-008-0196-5