Inhibition of Eukaryotic Translation Elongation by Cycloheximide and Lactimidomycin

Although the protein synthesis inhibitor cycloheximide (CHX) has been known for decades, its precise mechanism of action remains incompletely understood. The glutarimide portion of CHX is seen in a family of structurally related natural products including migrastatin, isomigrastatin and lactimidomyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider-Poetsch, Tilman, Ju, Jianhua, Eyler, Daniel E, Dang, Yongjun, Bhat, Shridhar, Merrick, William C, Green, Rachel, Shen, Ben, Liu, Jun O
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831214/
https://www.ncbi.nlm.nih.gov/pubmed/20118940
http://dx.doi.org/10.1038/nchembio.304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831214/
https://www.ncbi.nlm.nih.gov/pubmed/20118940
http://dx.doi.org/10.1038/nchembio.304

Ejemplares similares