Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM

Helix 38 (H38) of the large ribosomal subunit, with a length of 110 Å, reaches the small subunit through intersubunit bridge B1a. Previous cryo-EM studies revealed that the tip of H38 moves by more than 10 Å from the non-ratcheted to the ratcheted state of the ribosome while mutational studies impli...

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Detalles Bibliográficos
Autores principales: Réblová, Kamila, Rázga, Filip, Li, Wen, Gao, Haixiao, Frank, Joachim, Šponer, Jiří
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831300/
https://www.ncbi.nlm.nih.gov/pubmed/19952067
http://dx.doi.org/10.1093/nar/gkp1057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831300/
https://www.ncbi.nlm.nih.gov/pubmed/19952067
http://dx.doi.org/10.1093/nar/gkp1057

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